Cold sores normally first occur on or near your lip. They are caused by a type of herpes virus that is highly contagious and are often caught in childhood from someone who is infected. The virus lies dormant until it is activated, usually at a most inconvenient moment, and starts by tingling or burning near where the blister is going to occur. Within a few hours one or more small blisters form, often swelling the surrounding area, giving rise to a throbbing painful sore.